Neutraceuticals and Medicinal Plants

- Nutraceuticals and Medicinal Plants

  1. Lindinger MI, MacNicol JM, Karrow N, Pearson W. (2017). Effects of a novel dietary supplement on indices of muscle injury and articular gag release in horses. Journal of Equine Veterinary Science 48:52-60.
    https://doi.org/10.1016/j.jevs.2016.08.016
  2. Pearson W, MacNicol J. (2017). Acute effects of a single-dose nutritional product on stress response and task completion in horses. Journal of Equine Veterinary Science 51:86–91.
    https://doi.org/10.1016/j.jevs.2017.01.001
  3. MacNicol J, Lindinger MI, Pearson W. (2017) A Cucumis melo extract reduces inflammation systemically and within the joint following an exercise test in horses. Journal of Equine Veterinary Science 52, 71-72.
    https://www.j-evs.com/article/S0737-0806(17)30204-6/abstract
  4. Lindinger MI. (2016) Reduced dental plaque formation in dogs drinking a solution containing natural antimicrobial herbal enzymes and organic matcha green tea. Scientifica (Cairo). 2016:2183623
    https://www.hindawi.com/journals/scientifica/2016/2183623/
  5. Lindinger MI, Pearson W. (2015) Ergogenics & supplements for performance horses: recent innovations. In: Proceedings of the 7th European Equine Health & Nutrition Congress. Feeding the Equine Athlete.
    http://www.equine-congress.com/en/proceedings
  6. Lindinger MI, Anderson SC. (2014)  Seventy day safety assessment of an orally ingested, l-glutamine-containing oat and yeast supplement for horses. Regul Toxicol Pharmacol. 2014 Oct;70(1):304-11. doi:10.1016/j.yrtph.2014.07.011.
    https://www.sciencedirect.com/science/article/pii/S0273230014001664
  7. Lindinger MI, Ecker GL. (2013) Gastric emptying, intestinal absorption of electrolytes and exercise performance in electrolyte-supplemented horses. Exp Physiol 98(1):193-206. doi: 0.1113/ expphysiol. 2012.065185.
     https://physoc.onlinelibrary.wiley.com/doi/full/10.1113/expphysiol.2012.065185
  8. Pearson W, Lindinger MI. (2011) Antioxidant, anti-inflammatory and anticatabolic potential of rosmarinic acid and high-rosmarinic acid mint (Mentha spicata) in osteoarthritis. In Arthritis: Pathophysiology, Prevention, and Therapeutics. Bagchi D, Moriyama H, Raychaudhuri SP, eds. Boca Raton: CRC Press. 
    http://www.crcpress.com/product/isbn/9781439816868
  9. Pearson W, Lindinger MI. (2011) The anti-arthritic potential of green lipped mussel and other marine-based nutraceuticals. In Arthritis: Pathophysiology, Prevention, and Therapeutics.Bagchi D, Moriyama H, Raychaudhuri SP, eds. Boca Raton, FL: CRC Press. 
    http://www.crcpress.com/product/isbn/9781439816868
  10. Pearson W, Fletcher RS, Kott LS. (2012) Oral rosmarinic acid-enhanced Mentha spicata modulates synovial fluid biomarkers of inflammation in horses challenged with intra-articular LPS. J Vet Pharmacol Ther 35(5):495-502.
     http://www.ncbi.nlm.nih.gov/pubmed/22070392
  11. Pearson W, Lindinger MI. (2010) Evidence-based botanicals in North America. In: Ethnoveterinary Botanical Medicine: Herbal Medicines for Animal Health. Katerere DR, Luseba D, eds. Boca Raton, FL: CRC Press.
    http://www.crcpress.com/product/isbn/9781420045604
  12. Pearson W, Fletcher RS, Kott LS, Hurtig MB. (2010) Protection against LPS-induced cartilage inflammation and degradation provided by a biological extract of Mentha spicataBMC Complement Altern Med 10:19.
     http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2874512/
  13. Pearson W, Lindinger MI. (2009) Low quality of evidence for glucosamine-based nutraceuticals in equine lameness: a review of in vivo studies. Equine Vet J 41(7):706-712. 
    http://www.ncbi.nlm.nih.gov/pubmed/19927591
  14. Pearson W, Orth MW, Lindinger MI. (2009) Evaluation of inflammatory responses induced via intra-articular injection of interleukin-1 in horses receiving a dietary nutraceutical and assessment of the clinical effects of long-term nutraceutical administration. Am J Vet Res 70(7):848-861. 
    http://www.ncbi.nlm.nih.gov/pubmed/19566470
  15. Pearson W, Orth MW, Karrow NA, Lindinger MI. (2008) Effects of simulated digests of Biota orientalis and a dietary nutraceutical on interleukin-1-induced inflammatory responses in cartilage explants. Am J Vet Res 69(12):1560-1568
    http://www.ncbi.nlm.nih.gov/pubmed/19046001
  16. Pearson W, Lindinger MI. (2008) Simulated digest of a nutraceutical composite (HyalCare) modifies effect of IL-1 in a cartilage explant model of inflammation. J Vet Pharmacol Ther31:268–271.
     http://www.ncbi.nlm.nih.gov/pubmed/18471150
  17. Pearson W, Lindinger MI. (2008) Critical review of research evaluating glucosamine-based nutraceuticals for treatment of joint pain and degenerative joint disease in horses. Proceedings of the 4th European Equine Health & Nutrition Congress, April 18-19, 2008 – Wageningen University and Research Centre, Wageningen, the Netherlands. Page 81-91.
  18. Lindinger MI, Pearson W. (2008) Nutraceutical approaches to maintaining and improving health in performance horses. Proceedings of the 44th Eastern Nutrition Conference.
  19. Pearson W, Lindinger MI. (2008) Critical review of equine research evaluating glucosamine based nutraceuticals for treatment of joint pain and degenerative joint disease in horses. Proceedings of the Mid-Atlantic Nutrition Conference. pp. 184-191.
  20. Pearson W, Orth MW, Karrow NA, MacLusky N, Lindinger MI. (2007) Anti-inflammatory and chondroprotective effects of nutraceuticals in a cartilage explant model of inflammation. Mol Nutr Food Res 51(8):1020-1030.
     http://www.ncbi.nlm.nih.gov/pubmed/17639996
  21. Pearson W, Orth MW, Lindinger MI. (2007) Differential anti-inflammatory and chondroprotective effects of simulated digests of indomethacin and an herbal composite (MobilityTM) in a cartilage explant model of articular inflammation. J Vet Pharmacol Ther 30(6):523-533. 
    http://www.ncbi.nlm.nih.gov/pubmed/17991220
  22. Pearson W, Charch A, Brewer D, Clarke AF. (2007) Pilot study investigating the ability of an herbal composite to alleviate clinical signs of respiratory dysfunction in horses with recurrent airway obstruction. Can J Vet Res 71:145-151. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1829186/
  23. Pearson W. (2007) PhD Thesis. Development of in vitro and in vivo methods to evaluate putative dietary nutraceuticals. Department of Biomedical Sciences, Ontario Veterinary College, University of Guelph. Guelph, ON, Canada. http://www.collectionscanada.gc.ca/obj/thesescanada/vol2/002/NR36118.PDF
  24. Pearson W, Omar S, Clarke AF. (2007) Low-dose ginseng (Panax quinquefolium) modulates the course and magnitude of the antibody response to vaccination against Equid herpesvirus 1in horses. Can J Vet Res 71(3):213-217. 
    http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1899868/pdf/cjvr71_pg213.pdf
  25. Pearson W, Boermans HJ, Bettger WJ, McBride BW, Lindinger MI. (2005) Association of maximum voluntary intake of freeze dried garlic with Heinz body anemia in horses. Am J Vet Res66:457-465. 
    http://www.ncbi.nlm.nih.gov/pubmed/15822591
  26. Pearson W. (2004) The Science of Botanicals in Equine Health and Disease. Proceedings of the 2nd European Equine Health & Nutrition Congress.
  27. Pearson W. (2004) Veterinary applications of Echinacea sp: research in horses, cattle, poultry and swine. In Echinacea. The Genus Echinacea. Medicinal and Aromatic Plants—Industrial Profiles. Miller SC, ed. Boca Raton, FL: CRC Press. http://books.google.ca/books/about/Echinacea.html?id=WT48zTwLa9AC&redir_esc=y
  28. Pearson W. (2003) MSc Thesis. Garlic (Allium sativum) for horses: in vitro antibacterial activity and in vivo toxicity. Department of Human Health and Nutritional Sciences, Ontario Agriculture College, University of Guelph. Guelph, ON, Canada. http://sunzi.lib.hku.hk/ER/detail/hkul/3519654
  29. O’Neill W, McKee S, Clarke AF. (2002) Flaxseed (Linum usitatissimum) supplementation associated with reduced skin test lesional area in horses with Culicoides hypersensitivity. Can J Vet Res 66:272-277. 
    http://www.ncbi.nlm.nih.gov/pmc/articles/PMC227015/
  30. O’Neill W, McKee S, Clarke AF. (2002) Immunologic and haematinic consequences of feeding a standardized echinacea (Echinacea angustifolia) extract to healthy horses. Equine Vet J34(3):222-227.
     http://www.ncbi.nlm.nih.gov/pubmed/12108738
  31. Pearson-O’Neill W. (2001) Industry implications of commodity research: case study of ginseng. J Nutraceuticals Funct Med Foods 3(3):107-112.
  32. Pearson-O’Neill W. (2001) Improving immune function with ginseng. J Nutraceuticals Funct Med Foods 3(3):113.
  33. Pearson W. (2000) Pyrrolizidine alkaloids in higher plants: hepatic veno-occlusive disease associated with chronic consumption. J Nutraceuticals Funct Med Foods 3(1):87-96.
  1. Pearson W, McKee S, Clarke AF. (1999) Effect of a proprietary herbal product on equine joint disease. J Nutraceuticals Funct Med Foods 2(2):31-46.

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