Evidence Based Research

Research on Nutraceutical Ingredients and Nutraceutical Supplements

The Nutraceutical Alliance is committed to excellence in research design and execution and offer a wide range of research and development services for nutraceutical ingredients, nutraceutical supplements, health supplements, pharmacologics and functional foods.

Research Capabilities

Benefits of conducting research with the Nutraceutical Alliance include:

  • access to research animals and facilities that meet all regulatory requirements for animal care and use
  • retaining intellectual property rights to your research data
  • flexibility on public domain publishing
  • rapid turnaround times for contract researchs
  • access to global experts in canine cognitive / nutritional physiology and health

Ingredient Selection:

Based on your desired health goals for your nutraceutical supplement product, we will screen scientific databases for the best natural and beneficial nutraceutical ingredients. Ingredients are selected on the basis of evidence based research demonstrating efficacy (function) and safety. Sometimes ingredients can be selected because they already have the desired level of regulatory approval. A single ingredient sometimes provide a stand-alone nutraceutical supplement, or ingredients can be combined so that additive or synergistic health benefits can be obtained.

Product Development

We can assist with selecting a combination of ingredients based on the desired health outcome(s), interactions with medications, regulatory compliance, and budget. The nutraceutical manufacturing process also determines which ingredients can be used. Heating, extrusion, pressure and oxygen are a few examples of physical processes that can alter or damage ingredients during manufacture. We can also assist with selection of best processing, with excipient materials for materials flow / handling, moisture absorbance, anti-oxidant and bulking. The proportion of each ingredient with respect to the others in a product is usually important. This alone can differentiate an excellent nutraceutical supplement from a poor one.

Nutraceutical Supplement Testing

Nutraceutical supplement testing can be in the areas of nutrition, health and toxicology. We can use physiologically representative tissue and organ screening models to determine initial safety and function, prior to studies being performed on animals. 
Existing nutraceutical supplements and ingredients can also be tested for levels of key bioactive component as well as for contaminants.

Acute Safety Studies and Chronic Safety Studies

Scientific evidence must already exist for the safety of each ingredient prior to a nutraceutical supplement being tested in the target species. When safety of an ingredient in the target species is not known, safety studies using the ingredient alone must be performed and shown to be safe at well above the desired inclusion level prior to its inclusion in a product.


If the product is orally consumed, then it needs to taste good.

Function and Efficacy

Just because the scientific evidence suggests that an ingredient blend should work in a certain way, this needs to be verified. Sometimes added benefits are seen, and sometimes the product does not work as planned and needs to be changed.

Bioequivalence: Both Nutraceutical and Pharmaceutical

Bioequivalence studies test, using the same animals in a cross-over design, if two different products exhibit similar properties with respect to selected pharmacokinetic parameters such as absorption, bioavailability, tissue and organ distribution, action on target tissues, and health effects.

Examples of some Completed Projects

- Services

Nutraceutical Supplement Design

The Nutraceutical Alliance will guide you to developing effective and safe nutraceutiacal supplements and foods. The process begins by analysing your needs, then selecting nutraceutical ingredients backed by evidence based research. The Nutraceutical Alliance will help you create innovative, effective and safe health supplements and foods.

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Nutraceutical Evidence Based Research

Only the best nutraceutical supplements are backed by evidence based research. Ideally we want science based medicine. The Nutraceutical Alliance either does or assists with supplement research, including design of supplement function studies, supplement safety studies, execution of studies, and generating evidence based research.

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Regulatory Affairs

The Nutraceutical Alliance will prepare your nutraceutical supplement regulatory dossiers and related documentation for FDA, CVM, AAFCO, NASC, Health Canada, EFSA. We will interface with regulatory agencies on your behalf.

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Nutraceuticals Training and Education

Knowledge is power. The Nutraceutical Alliance is able to provide tailor-made packages for education and training for private label manufacturers, supplement designers, marketing and sales personnel, as well as executives and academics.

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Nutraceutical Ingredient and Supplement Safety

Knowledge is power. The Nutraceutical Alliance is able to provide tailor-made packages for education and training for private label manufacturers, supplement designers, marketing and sales personnel, as well as executives and academics.

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- Looking for more?

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New, interesting, current and relevant things in the nutraceuticals world, the Nutraceutical Alliance, and wellness for humans, dogs, cats and horses.

Design Nutraceutical Supplements

Evidence-based research to select key ingredients that work together, safely and effectively to support a broad range of health needs including g.i., immune, skin, respiratory, joint and muscle.

Contact Us

Let us know how the Nutraceutical Alliance can help you with nutraceutical supplement needs.
Contact us for more information.

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